Substance Information

In ZINC since Heavy atoms Benign functionality
October 3rd, 2005 7 Yes

Other Names:

"DL-Serine, 99%"

"L-Serine, 99%"

(+/-)-2-Amino-3-hydroxypropionic acid


(-)-Serine; (S)-2-amino-3-hydroxy-Propanoate; (S)-2-amino-3-hydroxy-Propanoic acid; (S)-2-Amino-3-hydroxypropanoate; (S)-2-Amino-3-hydroxypropanoic acid; (S)-a-Amino-b-hydroxypropionate; (S)-a-Amino-b-hydroxypropionic acid; (S)-alpha-Amino-beta-hydroxypro

(-)-Serine; (S)-2-Amino-3-hydroxypropanoate; (S)-2-Amino-3-hydroxypropanoic acid; (S)-2-amino-3-hydroxy-Propanoate; (S)-2-amino-3-hydroxy-Propanoic acid; (S)-Serine; (S)-a-Amino-b-hydroxypropionate; (S)-a-Amino-b-hydroxypropionic acid; (S)-alpha-Amino-bet

(-)-Serine;(S)-2-amino-3-hydroxy-Propanoate;(S)-2-amino-3-hydroxy-Propanoic acid;(S)-2-Amino-3-hydroxypropanoate;(S)-2-Amino-3-hydroxypropanoic acid;(S)-a-Amino-b-hydroxypropionate;(S)-a-Amino-b-hydroxypropionic acid;(S)-alpha-Amino-beta-hydroxypropionate

(-)-Serine;(S)-2-Amino-3-hydroxypropanoate;(S)-2-Amino-3-hydroxypropanoic acid;(S)-2-amino-3-hydroxy-Propanoate;(S)-2-amino-3-hydroxy-Propanoic acid;(S)-Serine;(S)-a-Amino-b-hydroxypropionate;(S)-a-Amino-b-hydroxypropionic acid;(S)-alpha-Amino-beta-hydrox

(2S)-2-amino-3-hydroxypropanoate; L-serine anion

(2S)-2-amino-3-hydroxypropanoic acid; (S)-(-)-serine; (S)-2-amino-3-hydroxypropanoic acid; (S)-alpha-Amino-beta-hydroxypropionic acid; (S)-serine; L-(-)-serine; L-3-Hydroxy-2-aminopropionic acid; L-Ser; L-Serin; SERINE; beta-Hydroxy-L-alanine; beta-Hydrox


(S)-2-(Boc-amino)-3-hydroxypropionic acid hydrate

(S)-2-Amino-3-hydroxypropanoic acid

(S)-2-Amino-3-hydroxypropanoic acid hydrochloride

(S)-2-Amino-3-hydroxypropanoic acid; (S)-Serine; 2-Amino-3-hydroxypropanoic acid; 2-Amino-3-hydroxypropanoic acid, (S)-; 2-Amino-3-hydroxypropionic acid; BRN 1721404; EINECS 200-274-3; HSDB 680; L-Serine; LS-144975; NSC 118365; Propanoic acid, 2-amino-3-h

(S)-2-Amino-3-hydroxypropanoic acid; (S)-Serine; 2-Amino-3-hydroxypropanoic acid; 2-Amino-3-hydroxypropanoic acid, (S)-; 2-Amino-3-hydroxypropionic acid; L-2-Amino-3-hydroxypropionic acid; L-3-Hydroxy-alanine; L-Serine; Propanoic acid, 2-amino-3-hydroxy-,


(S)-2-Amino-3-hydroxypropionic acid

(S)-a-Amino-b-hydroxypropionic acid



2-Amino-3-hydroxypropanoic acid

2-Amino-3-hydroxypropionic acid

2-Amino-3-hydroxypropionic acid; 3-Hydroxyalanine; 302-84-1; C00716; DL-Serine; Serine



56-45-1; D00016; L-Serine (JP16); Serine (USP)

56-45-1; L-ser; L-serine; ser; serine


Bis(L-serinato)cobalt dihydrate; Cobalt, bis(L-serinato)-, dihydrate; Cobalt, bis(L-serinato-N,O(sup 1),O(sup 3))-, dihydrate, L-; LS-54556


CHEBI:45440; CHEBI:45451; CHEBI:45677; CHEBI:45590; CHEBI:45597; CHEBI:13167; CHEBI:21387; CHEBI:6301



DL-Serine methyl ester hydrochloride

DL-Serine, 99%




L-3-Hydroxy-2-aminopropionic acid



L-Serine hydrochloride

L-Serine [56-45-1]

L-Serine, 99%

L-SERINE, [3-14 C]


L-SERINE; [56-45-1]

Methyl-DL-serine hydrochloride






N-Boc-L-serine hydrate, 98%



Serine (INN

Serine, l-[3-3h]

Store at 0-5C



Download: MOL2 SDF SMILES Flexibase



Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -3.67 -3.07 -34.14 4 4 0 88 105.093 2
Hi High (pH 8-9.5) -3.67 -3.4 -42.43 3 4 -1 86 104.085 2

Vendor Notes

Note Type Comments Provided By
UniProt Database Links 032R_FRG3G; 049R_IIV3; 110R_IIV3; 1433B_BOVIN; 1433B_HUMAN; 1433B_MACFA; 1433B_MOUSE; 1433B_PONAB; 1433B_RAT; 1433B_SHEEP; 1433F_BOVIN; 1433F_HUMAN; 1433F_MOUSE; 1433F_RAT; 1433T_HUMAN; 1433Z_BOVIN; 1433Z_HUMAN; 1433Z_MOUSE; 1433Z_PONAB; 1433Z_RAT; 1433Z_ ChEBI
Melting_Point 214-224? dec. Alfa-Aesar
Melting_Point 214-224° dec. Alfa-Aesar
MP 222 °C (dec.)(lit.) Indofine
MP 238 - 240 Enamine Building Blocks
MP 238...240 Enamine Building Blocks
Mp [°C] 240 Acros Organics
MP 240°(dec.) Oakwood Chemical
ALOGPS_SOLUBILITY 4.80e+02 g/l DrugBank-nutriceuticals
purity 9.500000000000000e+001 Enamine Building Blocks Enamine Building Blocks
Purity 95% Fluorochem
Purity 98% Fluorochem
Purity 99% Fluorochem
Melting_Point ca 240? dec. Alfa-Aesar
Melting_Point ca 240° dec. Alfa-Aesar
Patent Database Links EP0928790; EP1127869; EP1135995; EP1422218; EP1568283; EP1609462; EP1616963; EP1627884; EP1632233; EP1657249; EP1762232; EP1844784; EP1849466; EP1869977; EP1938798; EP1946776; EP1983044; US2003064429; US2003083383; US2003220404; US2004034080; US2005101540 ChEBI
SOLUBILITY H2O: 50 mg/mL Indofine
Reactome Database Links REACT_11108; REACT_111140; REACT_111222; REACT_11159; REACT_115816; REACT_115834; REACT_115874; REACT_120730; REACT_121084; REACT_13449; REACT_13455; REACT_13482; REACT_13531; REACT_13564; REACT_13590; REACT_13593; REACT_13618; REACT_13745; REACT_14802; R ChEBI
S phrase S24/25: Avoid contact with skin and eyes. Acros Organics
Notes USP, pyrogen freeCell culture tested Apollo Scientific Bioactives

Activity (Go SEA)

Direct Reactome Annotations (via ChEBI)

Description Species
Amino acid transport across the plasma membrane
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Antigen processing: Ubiquitination & Proteasome degradation
Cross-presentation of soluble exogenous antigens (endosomes)
Cysteine formation from homocysteine
Cysteine synthesis from O-acetylserine
Cytosolic tRNA aminoacylation
Degradation of cysteine and homocysteine
Endosomal/Vacuolar pathway
ER-Phagosome pathway
Glutathione synthesis and recycling
Metabolism of folate and pterines
Mitochondrial tRNA aminoacylation
Na+/Cl- dependent neurotransmitter transporters
Proton/oligonucleotide cotransporters
Serine biosynthesis
Sphingolipid de novo biosynthesis
Sphingolipid metabolism
Synthesis of PS

Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.