UCSF

ZINC13450933

Substance Information

In ZINC since Heavy atoms Benign functionality
June 19th, 2008 16 No

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) -1.02 -1.34 -93.24 0 7 -2 123 242.212 3

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
P4HTM-1-E Hypoxia-inducible Factor Prolyl 4-hydroxylase (cluster #1 Of 1), Eukaryotic Eukaryotes 1800 0.50 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
P4HTM_HUMAN Q9NXG6 Hypoxia-inducible Factor Prolyl 4-hydroxylase, Human 1800 0.50 Binding ≤ 10μM

Analogs ( Draw Identity 99% 90% 80% 70% )