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5HT1D_HUMAN - Serotonin 1d (5-HT1d) Receptor, Human | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF

Serotonin 1d (5-HT1d) Receptor, Human (1,086 Compounds)

Swissprot:
5HT1D_HUMAN
Stitch:
5HT1D_HUMAN
UniProt:
P28221
ChEMBL:
CHEMBL1983
Reactome:
REACT_19231
REACT_17064
PDB:
HTR1D

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 1,086 75 22 17
Binding ≤ 1μM 980 62 20 16
Functional ≤ 10μM 90 12 6 7

Reactome Network (2)

Reactome ID Description Species
REACT_19231 G alpha (i) signalling events Homo sapiens
REACT_17064 Serotonin receptors Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 434
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 843
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 43
5HT1F_HUMAN P30939 CHEMBL1805 Serotonin 1f (5-HT1f) Receptor, Human 73
5HT5A_HUMAN P47898 CHEMBL3426 Serotonin 5a (5-HT5a) Receptor, Human 62
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 5
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 3
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 4
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 23
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 20
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 29
ADCY1_HUMAN Q08828 CHEMBL2899 Brain Adenylate Cyclase 1, Human 1
ADCY2_HUMAN Q08462 CHEMBL3760 Adenylate Cyclase Type II, Human 1
ADCY8_HUMAN P40145 CHEMBL2960 Adenylate Cyclase Type VIII, Human 1
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 66
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 47
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 29
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 3
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 3
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 2
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 2
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 4

Serotonin receptors

Uniprot Swissprot Chembl Description Number Shared
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 434
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 843
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 43
5HT1F_HUMAN P30939 CHEMBL1805 Serotonin 1f (5-HT1f) Receptor, Human 73
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 79
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 68
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 121
5HT4R_HUMAN Q13639 CHEMBL1875 Serotonin 4 (5-HT4) Receptor, Human 19
5HT5A_HUMAN P47898 CHEMBL3426 Serotonin 5a (5-HT5a) Receptor, Human 62
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 74
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 99
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
5HT1D_MOUSE Q61224 CHEMBL4297 Serotonin 1d (5-HT1d) Receptor, Mouse 3 1 0 0
5HT1D_PIG P79400 CHEMBL4105 Serotonin 1d (5-HT1d) Receptor, Pig 28 5 5 4
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 269 101 45 44

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
5HT1D-1-E Serotonin 1d (5-HT1d) Receptor (cluster #1 Of 2), Eukaryotic 1,357 160 61 59
5HT1D-2-E Serotonin 1d (5-HT1d) Receptor (cluster #2 Of 2), Eukaryotic 38 10 2 1
Uniprot Swissprot Chembl Description Number Shared
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 843
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 430
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 178
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 174
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 138
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 121
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 115
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 98
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 94
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 79
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 74
5HT1F_HUMAN P30939 CHEMBL1805 Serotonin 1f (5-HT1f) Receptor, Human 73
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 73
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 68
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 66
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 66
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 63
5HT5A_HUMAN P47898 CHEMBL3426 Serotonin 5a (5-HT5a) Receptor, Human 62
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 50
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 47
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 46
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 43
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 33
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 33
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 29
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 29
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 28
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 27
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 24
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 23
5HT3A_HUMAN P46098 CHEMBL1899 Serotonin 3a (5-HT3a) Receptor, Human 20
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 20
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 19
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 19
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 19
5HT4R_HUMAN Q13639 CHEMBL1875 Serotonin 4 (5-HT4) Receptor, Human 18
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 17
ERG_HUMAN P11308 CHEMBL1293191 Transcriptional Regulator ERG, Human 16
5HT1A_MOUSE Q64264 CHEMBL3737 Serotonin 1a (5-HT1a) Receptor, Mouse 13
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 13
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 12
ADRB2_HUMAN P07550 CHEMBL210 Beta-2 Adrenergic Receptor, Human 12
5HT3B_HUMAN O95264 CHEMBL3895 Serotonin 3b (5-HT3b) Receptor, Human 11
5HT3E_HUMAN A5X5Y0 CHEMBL3812 Serotonin 3e (5-HT3e) Receptor, Human 11
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 10
5HT3C_HUMAN Q8WXA8 CHEMBL4795 Serotonin 3c (5-HT3c) Receptor, Human 10
5HT3D_HUMAN Q70Z44 CHEMBL4673 Serotonin 3d (5-HT3d) Receptor, Human 10
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 9
HRH2_HUMAN P25021 CHEMBL1941 Histamine H2 Receptor, Human 9
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 8
5HT3B_RAT Q9JJ16 CHEMBL3458 Serotonin 3b (5-HT3b) Receptor, Rat 8
5HT1D_PIG P79400 CHEMBL4105 Serotonin 1d (5-HT1d) Receptor, Pig 7
5HT5A_RAT P35364 CHEMBL4655 Serotonin 5a (5-HT5a) Receptor, Rat 7
DRD1_MOUSE Q61616 CHEMBL3071 Dopamine D1 Receptor, Mouse 7
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 7
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 6
ADA2A_BOVIN Q28838 CHEMBL4744 Alpha-2a Adrenergic Receptor, Bovin 6
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 6
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 6
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 5
5HT4R_CAVPO O70528 CHEMBL5017 Serotonin 4 (5-HT4) Receptor, Guinea Pig 5
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 5
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 5
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 5
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 5
HRH1_CAVPO P31389 CHEMBL3943 Histamine H1 Receptor, Guinea Pig 5
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 5
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 5
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 5
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 4
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 4
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 4
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 4
ADRB1_RAT P18090 CHEMBL3252 Beta-1 Adrenergic Receptor, Rat 4
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 4
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 4
5HT3A_MOUSE P23979 CHEMBL4972 Serotonin 3a (5-HT3a) Receptor, Mouse 3
5HT3B_MOUSE Q9JHJ5 CHEMBL3781 Serotonin 3b (5-HT3b) Receptor, Mouse 3
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 3
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 3
ADRB2_CANFA P54833 CHEMBL2289 Beta-2 Adrenergic Receptor, Canine 3
ADRB3_RAT P26255 CHEMBL4031 Beta-3 Adrenergic Receptor, Rat 3
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 3
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 3
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 3
NISCH_HUMAN Q9Y2I1 CHEMBL3923 Nischarin, Human 3
Z50588 Z50588 CHEMBL373 Canis Familiaris 3
Z50592 Z50592 CHEMBL374 Oryctolagus Cuniculus 3
5HT5A_MOUSE P30966 CHEMBL3597 Serotonin 5a (5-HT5a) Receptor, Mouse 2
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 2
ADA2A_MOUSE Q01338 CHEMBL4075 Alpha-2a Adrenergic Receptor, Mouse 2
ADA2A_PIG P18871 CHEMBL2350 Alpha-2a Adrenergic Receptor, Pig 2
ADA2B_MOUSE P30545 CHEMBL2405 Alpha-2b Adrenergic Receptor, Mouse 2
ADA2C_MOUSE Q01337 CHEMBL4826 Alpha-2c Adrenergic Receptor, Mouse 2
ADRB3_HUMAN P13945 CHEMBL246 Beta-3 Adrenergic Receptor, Human 2
GBRA1_HUMAN P14867 CHEMBL1962 GABA Receptor Alpha-1 Subunit, Human 2
GBRA2_HUMAN P47869 CHEMBL4956 GABA Receptor Alpha-2 Subunit, Human 2
GBRA3_HUMAN P34903 CHEMBL3026 GABA Receptor Alpha-3 Subunit, Human 2
GBRA4_HUMAN P48169 CHEMBL2472 GABA Receptor Alpha-4 Subunit, Human 2
GBRA5_HUMAN P31644 CHEMBL5112 GABA Receptor Alpha-5 Subunit, Human 2
GBRA6_HUMAN Q16445 CHEMBL2579 GABA Receptor Alpha-6 Subunit, Human 2
GBRB1_HUMAN P18505 CHEMBL4558 GABA Receptor Beta-1 Subunit, Human 2
GBRB2_HUMAN P47870 CHEMBL1920 GABA Receptor Beta-2 Subunit, Human 2
GBRB3_HUMAN P28472 CHEMBL1847 GABA Receptor Beta-3 Subunit, Human 2
GBRD_HUMAN O14764 CHEMBL3591 GABA Receptor Delta Subunit, Human 2
GBRE_HUMAN P78334 CHEMBL4635 GABA Receptor Epsilon Subunit, Human 2
GBRG1_HUMAN Q8N1C3 CHEMBL4044 GABA Receptor Gamma-1 Subunit, Human 2
GBRG2_HUMAN P18507 CHEMBL1788 GABA Receptor Gamma-2 Subunit, Human 2
GBRG3_HUMAN Q99928 CHEMBL2739 GABA Receptor Gamma-3 Subunit, Human 2
GBRP_HUMAN O00591 CHEMBL3506 GABA Receptor Pi Subunit, Human 2
GBRT_HUMAN Q9UN88 CHEMBL2843 GABA Receptor Theta Subunit, Human 2
HRH3_CAVPO Q9JI35 CHEMBL5076 Histamine H3 Receptor, Guinea Pig 2
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 2
HRH4_RAT Q91ZY1 CHEMBL4468 Histamine H4 Receptor, Rat 2
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 2
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 2
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 2
5HT2A_MOUSE P35363 CHEMBL5377 Serotonin 2a (5-HT2a) Receptor, Mouse 1
5HT2B_MOUSE Q02152 CHEMBL2583 Serotonin 2b (5-HT2b) Receptor, Mouse 1
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 1
5HT4R_RAT Q62758 CHEMBL4317 Serotonin 4 (5-HT4) Receptor, Rat 1
ACM5_RAT P08911 CHEMBL277 Muscarinic Acetylcholine Receptor M5, Rat 1
ADA1B_MESAU P18841 CHEMBL3122 Alpha-1b Adrenergic Receptor, Mesau 1
ADA2B_BOVIN O77700 CHEMBL3523 Alpha-2b Adrenergic Receptor, Bovin 1
ADCY1_HUMAN Q08828 CHEMBL2899 Brain Adenylate Cyclase 1, Human 1
ADCY2_HUMAN Q08462 CHEMBL3760 Adenylate Cyclase Type II, Human 1
ADCY8_HUMAN P40145 CHEMBL2960 Adenylate Cyclase Type VIII, Human 1
AOFA_RAT P21396 CHEMBL3358 Monoamine Oxidase A, Rat 1
AOFB_RAT P19643 CHEMBL2993 Monoamine Oxidase B, Rat 1
GNRHR_HUMAN P30968 CHEMBL1855 Gonadotropin-releasing Hormone Receptor, Human 1
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 1
HRH2_CAVPO P47747 CHEMBL2882 Histamine H2 Receptor, Guinea Pig 1
HRH2_RAT P25102 CHEMBL4654 Histamine H2 Receptor, Rat 1
MT3_HUMAN P25713 CHEMBL1250357 Metallothionein-3, Human 1
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 1
Q63380_RAT Q63380 CHEMBL6184 Transporter, Rat 1
S22A1_HUMAN O15245 CHEMBL5685 Solute Carrier Family 22 Member 1, Human 1
SC6A3_BOVIN P27922 CHEMBL2986 Dopamine Transporter, Bovin 1
SC6A3_MACFA Q9GJT6 CHEMBL5032 Dopamine Transporter, Macfa 1
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 1
SC6A4_MOUSE Q60857 CHEMBL4642 Serotonin Transporter, Mouse 1
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 1
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 1
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 1
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 1
UR2R_HUMAN Q9UKP6 CHEMBL3764 Urotensin II Receptor, Human 1
Z100251 Z100251 CHEMBL612442 Monoclonal Antibody (mAb) 2E2 1
Z50796 Z50796 CHEMBL614874 Monkey 1
Z80334 Z80334 CHEMBL613828 NG108-15 (Neuroblastoma-glioma Hybrid Cells) 1