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5HT3C_HUMAN - Serotonin 3c (5-HT3c) Receptor, Human | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF

Serotonin 3c (5-HT3c) Receptor, Human (211 Compounds)

Swissprot:
5HT3C_HUMAN
Stitch:
5HT3C_HUMAN
UniProt:
Q8WXA8
ChEMBL:
CHEMBL4795
Reactome:
REACT_25387
PDB:
HTR3C

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 211 72 14 11
Binding ≤ 1μM 182 53 12 11
Functional ≤ 10μM 29 10 0 0

Reactome Network (1)

Reactome ID Description Species
REACT_25387 Ligand-gated ion channel transport Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
5HT3A_HUMAN P46098 CHEMBL1899 Serotonin 3a (5-HT3a) Receptor, Human 234
5HT3B_HUMAN O95264 CHEMBL3895 Serotonin 3b (5-HT3b) Receptor, Human 234
5HT3D_HUMAN Q70Z44 CHEMBL4673 Serotonin 3d (5-HT3d) Receptor, Human 234
5HT3E_HUMAN A5X5Y0 CHEMBL3812 Serotonin 3e (5-HT3e) Receptor, Human 210

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
5HT3C-1-E Serotonin 3c (5-HT3c) Receptor (cluster #1 Of 2), Eukaryotic 136 17 9 10
5HT3C-2-E Serotonin 3c (5-HT3c) Receptor (cluster #2 Of 2), Eukaryotic 75 55 5 1
Uniprot Swissprot Chembl Description Number Shared
5HT3A_HUMAN P46098 CHEMBL1899 Serotonin 3a (5-HT3a) Receptor, Human 234
5HT3B_HUMAN O95264 CHEMBL3895 Serotonin 3b (5-HT3b) Receptor, Human 234
5HT3D_HUMAN Q70Z44 CHEMBL4673 Serotonin 3d (5-HT3d) Receptor, Human 234
5HT3E_HUMAN A5X5Y0 CHEMBL3812 Serotonin 3e (5-HT3e) Receptor, Human 210
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 58
5HT3B_RAT Q9JJ16 CHEMBL3458 Serotonin 3b (5-HT3b) Receptor, Rat 57
ACHA7_HUMAN P36544 CHEMBL2492 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Human 38
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 24
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 23
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 22
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 17
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 17
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 15
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 13
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 12
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 10
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 10
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 10
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 10
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 9
5HT4R_HUMAN Q13639 CHEMBL1875 Serotonin 4 (5-HT4) Receptor, Human 9
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 9
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 8
5HT1D_PIG P79400 CHEMBL4105 Serotonin 1d (5-HT1d) Receptor, Pig 8
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 8
5HT5A_HUMAN P47898 CHEMBL3426 Serotonin 5a (5-HT5a) Receptor, Human 8
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 8
ACHA7_RAT Q05941 CHEMBL4980 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Rat 6
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 6
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 6
5HT1F_HUMAN P30939 CHEMBL1805 Serotonin 1f (5-HT1f) Receptor, Human 5
ACHA7_MOUSE P49582 CHEMBL3365 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Mouse 5
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 5
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 5
5HT3A_MOUSE P23979 CHEMBL4972 Serotonin 3a (5-HT3a) Receptor, Mouse 4
5HT3B_MOUSE Q9JHJ5 CHEMBL3781 Serotonin 3b (5-HT3b) Receptor, Mouse 4
5HT4R_CAVPO O70528 CHEMBL5017 Serotonin 4 (5-HT4) Receptor, Guinea Pig 4
5HT3A_CAVPO O70212 CHEMBL3666 Serotonin 3a (5-HT3a) Receptor, Guinea Pig 3
5HT4R_RAT Q62758 CHEMBL4317 Serotonin 4 (5-HT4) Receptor, Rat 3
5HT5A_MOUSE P30966 CHEMBL3597 Serotonin 5a (5-HT5a) Receptor, Mouse 3
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 3
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 3
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 3
Z104283 Z104283 CHEMBL1907589 Neuronal Acetylcholine Receptor; Alpha4/beta2 3
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 2
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 2
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 2
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 2
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 2
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 2
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 2
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 2
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 2
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 2
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 2
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 2
CAC1C_RAT P22002 CHEMBL3762 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rat 2
CAC1D_RAT P27732 CHEMBL4132 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Rat 2
DRD1_PIG P50130 CHEMBL5067 Dopamine D1 Receptor, Pig 2
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 2
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 2
GASR_RAT P30553 CHEMBL3508 Cholecystokinin B Receptor, Rat 2
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 2
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 2
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 2
UROK_HUMAN P00749 CHEMBL3286 Urokinase-type Plasminogen Activator, Human 2
5HT1A_MOUSE Q64264 CHEMBL3737 Serotonin 1a (5-HT1a) Receptor, Mouse 1
5HT2A_MOUSE P35363 CHEMBL5377 Serotonin 2a (5-HT2a) Receptor, Mouse 1
5HT2B_MOUSE Q02152 CHEMBL2583 Serotonin 2b (5-HT2b) Receptor, Mouse 1
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 1
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 1
ACHA3_HUMAN P32297 CHEMBL3068 Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Human 1
ACHP_LYMST P58154 CHEMBL6084 Acetylcholine-binding Protein, Lymst 1
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 1
ADA2A_BOVIN Q28838 CHEMBL4744 Alpha-2a Adrenergic Receptor, Bovin 1
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 1
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 1
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 1
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 1
Z104282 Z104282 CHEMBL1907588 Acetylcholine Receptor; Alpha1/beta1/delta/gamma 1
Z104290 Z104290 CHEMBL1907596 Neuronal Acetylcholine Receptor; Alpha4/beta2 1
Z104292 Z104292 CHEMBL1907598 Integrin Alpha-V/beta-3 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1