UCSF

Androgen Receptor, Human (1,635 Compounds)

Swissprot:
ANDR_HUMAN
Stitch:
ANDR_HUMAN
UniProt:
P10275
ChEMBL:
CHEMBL1871
Reactome:
REACT_15525
PDB:
1E3G (DOCK)
1GS4 (DOCK)
1T5Z (DOCK)
1T63 (DOCK)
1T65 (DOCK)
1XJ7 (DOCK)
1XOW (DOCK)
1XQ3 (DOCK)
1Z95 (DOCK)
2AM9 (DOCK)
2AMA (DOCK)
2AMB (DOCK)
2AO6 (DOCK)
2AX6 (DOCK)
2AX7 (DOCK)
2AX8 (DOCK)
2AX9 (DOCK)
2AXA (DOCK)
2HVC (DOCK)
2OZ7 (DOCK)
2PIO (DOCK)
2PIP (DOCK)
2PIQ (DOCK)
2PIR (DOCK)
2PIT (DOCK)
2PIU (DOCK)
2PIV (DOCK)
2PIW (DOCK)
2PIX (DOCK)
2PKL (DOCK)
2PNU (DOCK)
2Q7I (DOCK)
2Q7J (DOCK)
2Q7K (DOCK)
2Q7L (DOCK)
2YHD (DOCK)
2YLO (DOCK)
2YLP (DOCK)
2YLQ (DOCK)
2Z4J (DOCK)
3B5R (DOCK)
3B65 (DOCK)
3B66 (DOCK)
3B67 (DOCK)
3B68 (DOCK)
3BTR (DOCK)
3L3X (DOCK)
3L3Z (DOCK)
3RLJ (DOCK)
3RLL (DOCK)
3ZQT (DOCK)
AR

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 1,635 98 33 25
Binding ≤ 1μM 1,334 89 32 24
Functional ≤ 10μM 1,125 70 24 23

Reactome Network (1)

Reactome ID Description Species
REACT_15525 Nuclear Receptor transcription pathway Homo sapiens
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ANDR_MOUSE P19091 CHEMBL3056 Androgen Receptor, Mouse 20 4 4 4
ANDR_RAT P15207 CHEMBL3072 Androgen Receptor, Rat 178 13 11 10

Clustered By Gene (0)

Clustered By Organism (3)

Code Description Substances Purchasable Natural In Man
ANDR-1-E Androgen Receptor (cluster #1 Of 4), Eukaryotic 1,182 18 8 11
ANDR-2-E Androgen Receptor (cluster #2 Of 4), Eukaryotic 358 59 30 19
ANDR-3-E Androgen Receptor (cluster #3 Of 4), Eukaryotic 115 3 0 1
ANDR-4-E Androgen Receptor (cluster #4 Of 4), Eukaryotic 194 29 6 5
Uniprot Swissprot Chembl Description Number Shared
PRGR_HUMAN P06401 CHEMBL208 Progesterone Receptor, Human 522
GCR_HUMAN P04150 CHEMBL2034 Glucocorticoid Receptor, Human 404
MCR_HUMAN P08235 CHEMBL1994 Mineralocorticoid Receptor, Human 209
ESR2_HUMAN Q92731 CHEMBL242 Estrogen Receptor Beta, Human 148
ESR1_HUMAN P03372 CHEMBL206 Estrogen Receptor Alpha, Human 134
Z80243 Z80243 CHEMBL614334 MDA-MB-453 (Breast Adenocarcinoma Cells) 33
MCR_RAT P22199 CHEMBL3507 Mineralocorticoid Receptor, Rat 18
Q5EM59_BOVIN Q5EM59 CHEMBL3953 Androgen Receptor, Bovin 18
ANDR_RAT P15207 CHEMBL3072 Androgen Receptor, Rat 17
CP17A_HUMAN P05093 CHEMBL3522 Cytochrome P450 17A1, Human 16
ANDR_MOUSE P19091 CHEMBL3056 Androgen Receptor, Mouse 14
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 11
NR1I2_HUMAN O75469 CHEMBL3401 Pregnane X Receptor, Human 6
VDR_HUMAN P11473 CHEMBL1977 Vitamin D Receptor, Human 6
GCR_RAT P06536 CHEMBL3368 Glucocorticoid Receptor, Rat 5
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 5
PRGR_RABIT P06186 CHEMBL3456 Progesterone Receptor, Rabit 4
PRGR_RAT Q63449 CHEMBL2596 Progesterone Receptor, Rat 4
Z80110 Z80110 CHEMBL613507 CV-1 (Kidney Cells) 4
GCR_MOUSE P06537 CHEMBL3144 Glucocorticoid Receptor, Mouse 3
SHBG_HUMAN P04278 CHEMBL3305 Testis-specific Androgen-binding Protein, Human 3
Z81170 Z81170 CHEMBL612518 LNCaP (Prostate Carcinoma) 3
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 2
ERG2_YEAST P32352 CHEMBL3224 C-8 Sterol Isomerase, Yeast 2
ESR1_RAT P06211 CHEMBL2724 Estrogen Receptor Alpha, Rat 2
ESR2_RAT Q62986 CHEMBL3021 Estrogen Receptor Beta, Rat 2
FABPL_RAT P02692 CHEMBL5738 Fatty Acid-binding Protein, Liver, Rat 2
GPBAR_HUMAN Q8TDU6 CHEMBL5409 G-protein Coupled Bile Acid Receptor 1, Human 2
PRGR_CHICK P07812 CHEMBL3304 Progesterone Receptor, Chick 2
S5A1_RAT P24008 CHEMBL3422 Steroid 5-alpha-reductase 1, Rat 2
S5A2_RAT P31214 CHEMBL5099 Steroid 5-alpha-reductase 2, Rat 2
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 2
SHBG_RAT P08689 CHEMBL4932 Testis-specific Androgen-binding Protein, Rat 2
THA_HUMAN P10827 CHEMBL1860 Thyroid Hormone Receptor Alpha, Human 2
Z80418 Z80418 CHEMBL612557 RAW264.7 (Monocytic-macrophage Leukemia Cells) 2
Z80491 Z80491 CHEMBL614163 SK-N-MC (Neuroepithelioma Cells) 2
Z80712 Z80712 CHEMBL614361 T47D (Breast Carcinoma Cells) 2
Z80951 Z80951 CHEMBL614822 NIH3T3 (Fibroblasts) 2
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 1
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 1
AA2BR_RAT P29276 CHEMBL2592 Adenosine A2b Receptor, Rat 1
ERR1_HUMAN P11474 CHEMBL3429 Estrogen-related Receptor Alpha, Human 1
ERR2_HUMAN O95718 CHEMBL3751 Estrogen-related Receptor Beta, Human 1
ESR1_BOVIN P49884 CHEMBL2930 Estrogen Receptor Alpha, Bovin 1
ESR1_MOUSE P19785 CHEMBL3065 Estrogen Receptor Alpha, Mouse 1
ESR2_MOUSE O08537 CHEMBL2995 Estrogen Receptor Beta, Mouse 1
GLNA_HUMAN P15104 CHEMBL4612 Glutamine Synthetase, Human 1
GPER_HUMAN Q99527 CHEMBL5872 G-protein Coupled Estrogen Receptor 1, Human 1
NR1H2_HUMAN P55055 CHEMBL4093 LXR-beta, Human 1
NR1H3_HUMAN Q13133 CHEMBL2808 LXR-alpha, Human 1
NR1H4_HUMAN Q96RI1 CHEMBL2047 Bile Acid Receptor FXR, Human 1
NR1H4_MOUSE Q60641 CHEMBL5343 Bile Acid Receptor, Mouse 1
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 1
THB_HUMAN P10828 CHEMBL1947 Thyroid Hormone Receptor Beta-1, Human 1
VP16_HHV11 P06492 CHEMBL4218 Alpha Trans-inducing Protein (VP16), Hhv11 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1
Z50607 Z50607 CHEMBL378 Human Immunodeficiency Virus 1 1
Z50652 Z50652 CHEMBL613740 Influenza A Virus 1
Z80453 Z80453 CHEMBL614897 SC-3 1