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CALM_HUMAN - Calmodulin, Human | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF

Calmodulin, Human (8 Compounds)

Swissprot:
CALM_HUMAN
Stitch:
CALM_HUMAN
UniProt:
P62158
ChEMBL:
CHEMBL6093
Reactome:
REACT_21346
REACT_20652
REACT_118700
REACT_172761
REACT_9000
REACT_9053
REACT_15408
REACT_15502
REACT_20642
REACT_20661
REACT_15334
REACT_12477
REACT_163834
REACT_1008
REACT_163919
REACT_318
REACT_20546
REACT_20558
REACT_150312
REACT_111176
REACT_200608
REACT_147867
REACT_228024
REACT_228016
PDB:
1AJI (DOCK)
1CDL (DOCK)
1CLL (DOCK)
1CTR (DOCK)
1IWQ (DOCK)
1J7O (DOCK)
1J7P (DOCK)
1K90 (DOCK)
1K93 (DOCK)
1L7Z (DOCK)
1LVC (DOCK)
1NKF (DOCK)
1PK0 (DOCK)
1S26 (DOCK)
1SK6 (DOCK)
1SW8 (DOCK)
1WRZ (DOCK)
1XFU (DOCK)
1XFV (DOCK)
1XFW (DOCK)
1XFX (DOCK)
1XFY (DOCK)
1XFZ (DOCK)
1Y6W (DOCK)
1YR5 (DOCK)
1YRT (DOCK)
1YRU (DOCK)
1ZOT (DOCK)
1ZUZ (DOCK)
2BE6 (DOCK)
2F3Y (DOCK)
2F3Z (DOCK)
2HF5 (DOCK)
2I08 (DOCK)
2JZI (DOCK)
2K0E (DOCK)
2K0F (DOCK)
2K0J (DOCK)
2K61 (DOCK)
2KNE (DOCK)
2KUG (DOCK)
2KUH (DOCK)
2L53 (DOCK)
2L7L (DOCK)
2R28 (DOCK)
2V01 (DOCK)
2V02 (DOCK)
2VAY (DOCK)
2W73 (DOCK)
2WEL (DOCK)
2X0G (DOCK)
2Y4V (DOCK)
3BYA (DOCK)
3DVE (DOCK)
3DVJ (DOCK)
3DVK (DOCK)
3DVM (DOCK)
3EWT (DOCK)
3EWV (DOCK)
3G43 (DOCK)
3HR4 (DOCK)
3O77 (DOCK)
3O78 (DOCK)
3OXQ (DOCK)
CALM1
CALM2
CALM3

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 8 3 4 2
Binding ≤ 1μM 2 1 1 1

Reactome Network (24)

Reactome ID Description Species
REACT_21346 Activation of Ca-permeable Kainate Receptor Homo sapiens
REACT_20652 Activation of CaMK IV Homo sapiens
REACT_118700 Antigen activates B Cell Receptor (BCR) leading to generation of second messenge Homo sapiens
REACT_172761 Ca2+ pathway Homo sapiens
REACT_9000 Calmodulin induced events Homo sapiens
REACT_9053 CaM pathway Homo sapiens
REACT_15408 Cam-PDE 1 activation Homo sapiens
REACT_15502 CaMK IV-mediated phosphorylation of CREB Homo sapiens
REACT_20642 CREB phosphorylation through the activation of CaMKII Homo sapiens
REACT_20661 CREB phosphorylation through the activation of CaMKK Homo sapiens
REACT_15334 DARPP-32 events Homo sapiens
REACT_12477 eNOS activation Homo sapiens
REACT_163834 FCERI mediated Ca+2 mobilization Homo sapiens
REACT_1008 Glycogen breakdown (glycogenolysis) Homo sapiens
REACT_163919 Inactivation, recovery and regulation of the phototransduction cascade Homo sapiens
REACT_318 Platelet degranulation Homo sapiens
REACT_20546 Ras activation uopn Ca2+ infux through NMDA receptor Homo sapiens
REACT_20558 Smooth Muscle Contraction Homo sapiens
REACT_150312 Synthesis of IP3 and IP4 in the cytosol Homo sapiens
REACT_111176 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation Homo sapiens
REACT_200608 Transcriptional activation of mitochondrial biogenesis Homo sapiens
REACT_147867 Translocation of GLUT4 to the plasma membrane Homo sapiens
REACT_228024 VEGFR2 mediated cell proliferation Homo sapiens
REACT_228016 VEGFR2 mediated vascular permeability Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 1
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 1
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 1
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 1
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 1

Ras activation uopn Ca2+ infux through NMDA receptor

Uniprot Swissprot Chembl Description Number Shared
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 1
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 1
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 1
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 1
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 1

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
CALM-1-E Calmodulin (cluster #1 Of 2), Eukaryotic 5 1 2 0
CALM-2-E Calmodulin (cluster #2 Of 2), Eukaryotic 3 2 2 2
Uniprot Swissprot Chembl Description Number Shared
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 2
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 2
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 2
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 2
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 2
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 2
PDR5_YEAST P33302 CHEMBL1697658 Pleiotropic ABC Efflux Transporter Of Multiple Drugs, Yeast 2
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 2
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 2
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 2
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 2
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 2
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 1
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 1
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 1
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 1
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 1
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 1
A3EZI9_9HEPC A3EZI9 CHEMBL4893 Hepatitis C Virus NS3 Protease/helicase, 9hepc 1
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 1
ADCY3_RAT P21932 CHEMBL4864 Adenylate Cyclase Type III, Rat 1
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 1
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 1
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 1
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 1
BGLR_RAT P06760 CHEMBL4814 Beta-glucuronidase, Rat 1
D4A3N4_RAT D4A3N4 CHEMBL2679 Brain Adenylate Cyclase 1, Rat 1
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 1
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 1
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 1
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 1
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 1
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 1
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 1
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 1
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 1
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 1
EBP_HUMAN Q15125 CHEMBL4931 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human 1
ERG2_YEAST P32352 CHEMBL3224 C-8 Sterol Isomerase, Yeast 1
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
LYSC1_RAT P00697 CHEMBL2297 Lysozyme C, Rat 1
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 1
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 1
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 1
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 1
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 1
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 1
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 1
PRIO_HUMAN P04156 CHEMBL4869 Prion Protein, Human 1
Q8CFM9_RAT Q8CFM9 CHEMBL3940 Adenylate Cyclase Type VII, Rat 1
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 1
TRPV1_RAT O35433 CHEMBL5102 Vanilloid Receptor, Rat 1
TYTR_TRYCR P28593 CHEMBL5131 Trypanothione Reductase, Trycr 1
Z104301 Z104301 CHEMBL1907607 GABA-A Receptor; Anion Channel 1
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 1
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1