C-8 Sterol Isomerase, Yeast (52 Compounds)


Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 52 27 25 22
Binding ≤ 1μM 38 20 20 17

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ERG7_YEAST P38604 CHEMBL5355 Lanosterol Synthase, Yeast 25 2 0 6

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
ERG2-1-F C-8 Sterol Isomerase (cluster #1 Of 2), Fungal 7 5 4 3
ERG2-2-F C-8 Sterol Isomerase (cluster #2 Of 2), Fungal 45 22 21 19
Uniprot Swissprot Chembl Description Number Shared
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 50
EBP_HUMAN Q15125 CHEMBL4931 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human 47
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 6
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 5
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 5
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 4
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 3
ESR1_RAT P06211 CHEMBL2724 Estrogen Receptor Alpha, Rat 3
ESR2_RAT Q62986 CHEMBL3021 Estrogen Receptor Beta, Rat 3
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 2
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 2
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 2
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 2
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 2
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 2
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 2
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 2
ANDR_HUMAN P10275 CHEMBL1871 Androgen Receptor, Human 2
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 2
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 2
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 2
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 2
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 2
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 2
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 2
EBP_CAVPO Q60490 CHEMBL5525 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Guinea Pig 2
ERG7_RAT P48450 CHEMBL3262 Lanosterol Synthase, Rat 2
ESR1_HUMAN P03372 CHEMBL206 Estrogen Receptor Alpha, Human 2
ESR2_HUMAN Q92731 CHEMBL242 Estrogen Receptor Beta, Human 2
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 2
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 2
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 2
S5A1_RAT P24008 CHEMBL3422 Steroid 5-alpha-reductase 1, Rat 2
S5A2_RAT P31214 CHEMBL5099 Steroid 5-alpha-reductase 2, Rat 2
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 2
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 2
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 2
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 2
Z100491 Z100491 CHEMBL613288 Sigma 2 Receptor 2
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 2
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 1
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 1
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 1
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 1
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 1
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 1
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 1
5HT2A_MOUSE P35363 CHEMBL5377 Serotonin 2a (5-HT2a) Receptor, Mouse 1
5HT2A_PIG P50129 CHEMBL2490 Serotonin 2a (5-HT2a) Receptor, Pig 1
5HT2B_MOUSE Q02152 CHEMBL2583 Serotonin 2b (5-HT2b) Receptor, Mouse 1
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 1
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 1
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 1
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 1
A3EZI9_9HEPC A3EZI9 CHEMBL4893 Hepatitis C Virus NS3 Protease/helicase, 9hepc 1
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 1
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 1
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 1
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 1
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 1
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 1
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 1
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 1
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 1
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 1
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 1
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 1
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 1
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 1
ANDR_MOUSE P19091 CHEMBL3056 Androgen Receptor, Mouse 1
ANDR_RAT P15207 CHEMBL3072 Androgen Receptor, Rat 1
AP2S1_RAT P62744 CHEMBL1697667 AP-2 Complex Subunit Sigma, Rat 1
BGLR_RAT P06760 CHEMBL4814 Beta-glucuronidase, Rat 1
CALM_HUMAN P62158 CHEMBL6093 Calmodulin, Human 1
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 1
CYSP_TRYCR P25779 CHEMBL3563 Cruzipain, Trycr 1
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 1
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 1
DRD1_PIG P50130 CHEMBL5067 Dopamine D1 Receptor, Pig 1
DRD2_CHLAE P52702 CHEMBL5456 Dopamine D2 Receptor, Chlae 1
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 1
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 1
FABPL_RAT P02692 CHEMBL5738 Fatty Acid-binding Protein, Liver, Rat 1
FDFT_HUMAN P37268 CHEMBL3338 Squalene Synthetase, Human 1
GCR_HUMAN P04150 CHEMBL2034 Glucocorticoid Receptor, Human 1
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 1
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 1
LEF_BACAN P15917 CHEMBL4372 Anthrax Lethal Factor, Bacan 1
LYSC1_RAT P00697 CHEMBL2297 Lysozyme C, Rat 1
MCR_HUMAN P08235 CHEMBL1994 Mineralocorticoid Receptor, Human 1
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 1
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 1
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 1
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 1
NMDE2_RAT Q00960 CHEMBL311 Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat 1
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 1
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 1
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 1
NMDZ1_RAT P35439 CHEMBL330 Glutamate (NMDA) Receptor Subunit Zeta 1, Rat 1
O77823_PIG O77823 CHEMBL3333 Phosphodiesterase 4A, Pig 1
PDE1A_HUMAN P54750 CHEMBL3421 Phosphodiesterase 1A, Human 1
PDE1B_HUMAN Q01064 CHEMBL4425 Phosphodiesterase 1B, Human 1
PDE1B_RAT Q01066 CHEMBL3665 Phosphodiesterase 1B, Rat 1
PDE1C_HUMAN Q14123 CHEMBL4619 Phosphodiesterase 1C, Human 1
PDR5_YEAST P33302 CHEMBL1697658 Pleiotropic ABC Efflux Transporter Of Multiple Drugs, Yeast 1
PLD1_HUMAN Q13393 CHEMBL2536 Phospholipase D1, Human 1
PLD2_HUMAN O14939 CHEMBL2734 Phospholipase D2, Human 1
PRGR_CHICK P07812 CHEMBL3304 Progesterone Receptor, Chick 1
PRGR_HUMAN P06401 CHEMBL208 Progesterone Receptor, Human 1
PRGR_RABIT P06186 CHEMBL3456 Progesterone Receptor, Rabit 1
Q4U254_9ENTO Q4U254 CHEMBL2857 Human Rhinovirus A Protease, 9ento 1
Q63380_RAT Q63380 CHEMBL6184 Transporter, Rat 1
Q72874_9HIV1 Q72874 CHEMBL243 Human Immunodeficiency Virus Type 1 Protease, 9hiv1 1
Q8AWE3_CHICK Q8AWE3 CHEMBL2669 Serine-threonine Protein Phosphatase 2A Regulatory Subunit, Chick 1
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 1
SHBG_HUMAN P04278 CHEMBL3305 Testis-specific Androgen-binding Protein, Human 1
SHH_HUMAN Q15465 CHEMBL5602 Sonic Hedgehog Protein, Human 1
THA_HUMAN P10827 CHEMBL1860 Thyroid Hormone Receptor Alpha, Human 1
THB_HUMAN P10828 CHEMBL1947 Thyroid Hormone Receptor Beta-1, Human 1
Z100267 Z100267 CHEMBL612409 Anti-estrogen Binding Site (AEBS) 1
Z104297 Z104297 CHEMBL1907603 Glutamate NMDA Receptor; GRIN1/GRIN2B 1
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 1
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 1