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OPRD_HUMAN - Delta Opioid Receptor, Human | ZINC Is Not Commercial - A database of commercially-available compounds
UCSF

Delta Opioid Receptor, Human (2,756 Compounds)

Swissprot:
OPRD_HUMAN
Stitch:
OPRD_HUMAN
UniProt:
P41143
ChEMBL:
CHEMBL236
Reactome:
REACT_19231
REACT_14819
PDB:
1OZC (DOCK)
2IQM (DOCK)
OPRD1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 2,756 80 45 46
Binding ≤ 1μM 2,115 60 34 40
Functional ≤ 10μM 222 7 8 5

Reactome Network (2)

Uniprot Swissprot Chembl Description Number Shared
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 5
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 4
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 2
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 2
5HT5A_HUMAN P47898 CHEMBL3426 Serotonin 5a (5-HT5a) Receptor, Human 3
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 1
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 5
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 5
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 3
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 4
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 3
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 2
CNR1_HUMAN P21554 CHEMBL218 Cannabinoid CB1 Receptor, Human 1
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 11
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 15
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 10
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 2
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 2
MTR1A_HUMAN P48039 CHEMBL1945 Melatonin Receptor 1A, Human 1
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 2005
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 2244
OPRX_HUMAN P41146 CHEMBL2014 Nociceptin Receptor, Human 385
PDYN_HUMAN P01213 CHEMBL2227 Proenkephalin B, Human 1
PE2R3_HUMAN P43115 CHEMBL3710 Prostanoid EP3 Receptor, Human 1

Peptide ligand-binding receptors

Uniprot Swissprot Chembl Description Number Shared
GASR_HUMAN P32239 CHEMBL298 Cholecystokinin B Receptor, Human 1
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 2005
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 2244
OPRX_HUMAN P41146 CHEMBL2014 Nociceptin Receptor, Human 385
PDYN_HUMAN P01213 CHEMBL2227 Proenkephalin B, Human 1
UR2R_HUMAN Q9UKP6 CHEMBL3764 Urotensin II Receptor, Human 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 359 21 12 16
OPRD_PIG P79291 CHEMBL4103 Delta Opioid Receptor, Pig 187 4 4 1
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 1,915 66 39 51

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
OPRD-1-E Delta Opioid Receptor (cluster #1 Of 3), Eukaryotic 4,915 142 74 93
OPRD-2-E Delta Opioid Receptor (cluster #2 Of 3), Eukaryotic 1 0 1 1
OPRD-3-E Delta Opioid Receptor (cluster #3 Of 3), Eukaryotic 4 2 0 0
Uniprot Swissprot Chembl Description Number Shared
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 2239
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 2005
OPRX_HUMAN P41146 CHEMBL2014 Nociceptin Receptor, Human 385
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 276
OPRK_CAVPO P41144 CHEMBL3952 Kappa Opioid Receptor, Guinea Pig 182
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 134
OPRM_CAVPO P97266 CHEMBL4354 Mu Opioid Receptor, Guinea Pig 112
OPRM_MOUSE P42866 CHEMBL2858 Mu Opioid Receptor, Mouse 83
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 67
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 56
OPRD_PIG P79291 CHEMBL4103 Delta Opioid Receptor, Pig 55
OPRM_BOVIN P79350 CHEMBL3041 Mu Opioid Receptor, Bovin 43
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 41
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 40
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 28
OPRK_MOUSE P33534 CHEMBL4329 Kappa Opioid Receptor, Mouse 23
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 23
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 15
Z50512 Z50512 CHEMBL369 Cavia Porcellus 14
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 13
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 13
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 13
SGMR1_MOUSE O55242 CHEMBL3465 Sigma Opioid Receptor, Mouse 13
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 11
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 10
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 10
Z50594 Z50594 CHEMBL375 Mus Musculus 10
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 9
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 9
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 9
CAC1C_HUMAN Q13936 CHEMBL1940 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Human 8
CAC1D_HUMAN Q01668 CHEMBL4138 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Human 8
CAC1F_HUMAN O60840 CHEMBL5593 Voltage-gated L-type Calcium Channel Alpha-1F Subunit, Human 8
CAC1S_HUMAN Q13698 CHEMBL3805 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Human 8
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 8
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 8
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 7
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 7
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 6
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 6
HRH2_HUMAN P25021 CHEMBL1941 Histamine H2 Receptor, Human 6
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 5
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 5
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 5
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 5
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 5
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 4
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 4
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 4
NMD3B_RAT Q8VHN2 CHEMBL282 Glutamate [NMDA] Receptor Subunit 3B, Rat 4
NMDE2_RAT Q00960 CHEMBL311 Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat 4
NMDE3_RAT Q00961 CHEMBL401 Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat 4
NMDE4_RAT Q62645 CHEMBL303 Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat 4
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 3
5HT5A_HUMAN P47898 CHEMBL3426 Serotonin 5a (5-HT5a) Receptor, Human 3
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 3
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 3
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 3
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 3
ADRB3_HUMAN P13945 CHEMBL246 Beta-3 Adrenergic Receptor, Human 3
NK2R_HUMAN P21452 CHEMBL2327 Neurokinin 2 Receptor, Human 3
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 3
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 2
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 2
5HT3A_HUMAN P46098 CHEMBL1899 Serotonin 3a (5-HT3a) Receptor, Human 2
5HT4R_HUMAN Q13639 CHEMBL1875 Serotonin 4 (5-HT4) Receptor, Human 2
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 2
ADRB2_HUMAN P07550 CHEMBL210 Beta-2 Adrenergic Receptor, Human 2
CAC1G_HUMAN O43497 CHEMBL4641 Voltage-gated T-type Calcium Channel Alpha-1G Subunit, Human 2
CAC1S_RAT Q02485 CHEMBL4108 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Rat 2
CCKAR_RAT P30551 CHEMBL2871 Cholecystokinin A Receptor, Rat 2
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 2
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 2
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 2
OPRX_RAT P35370 CHEMBL4503 Nociceptin Receptor, Rat 2
Q8CGM4_CAVPO Q8CGM4 CHEMBL5430 Mu-opioid Receptor, Guinea Pig 2
SCN2A_RAT P04775 CHEMBL3399 Sodium Channel Protein Type II Alpha Subunit, Rat 2
V1AR_HUMAN P37288 CHEMBL1889 Vasopressin V1a Receptor, Human 2
Z100254 Z100254 CHEMBL613295 Monoclonal Antibody (mAb) 3E7 2
5HT1D_PIG P79400 CHEMBL4105 Serotonin 1d (5-HT1d) Receptor, Pig 1
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 1
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 1
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 1
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 1
BACE1_HUMAN P56817 CHEMBL4822 Beta-secretase 1, Human 1
CA2D1_RAT P54290 CHEMBL3420 Voltage-gated Calcium Channel Alpha2/delta Subunit 1, Rat 1
CAC1B_HUMAN Q00975 CHEMBL4478 Voltage-gated N-type Calcium Channel Alpha-1B Subunit, Human 1
CAC1B_RAT Q02294 CHEMBL5107 Voltage-gated N-type Calcium Channel Alpha-1B Subunit, Rat 1
CAC1H_HUMAN O95180 CHEMBL1859 Voltage-gated T-type Calcium Channel Alpha-1H Subunit, Human 1
CAC1I_HUMAN Q9P0X4 CHEMBL5558 Voltage-gated T-type Calcium Channel Alpha-1I Subunit, Human 1
CACB1_RAT P54283 CHEMBL1075136 Voltage-dependent L-type Calcium Channel Subunit Beta-1, Rat 1
CCR5_MOUSE P51682 CHEMBL3676 C-C Chemokine Receptor Type 5, Mouse 1
CNR1_HUMAN P21554 CHEMBL218 Cannabinoid CB1 Receptor, Human 1
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 1
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 1
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 1
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 1
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 1
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 1
GASR_HUMAN P32239 CHEMBL298 Cholecystokinin B Receptor, Human 1
GBRA1_HUMAN P14867 CHEMBL1962 GABA Receptor Alpha-1 Subunit, Human 1
GBRA2_HUMAN P47869 CHEMBL4956 GABA Receptor Alpha-2 Subunit, Human 1
GBRA3_HUMAN P34903 CHEMBL3026 GABA Receptor Alpha-3 Subunit, Human 1
GBRA4_HUMAN P48169 CHEMBL2472 GABA Receptor Alpha-4 Subunit, Human 1
GBRA5_HUMAN P31644 CHEMBL5112 GABA Receptor Alpha-5 Subunit, Human 1
GBRA6_HUMAN Q16445 CHEMBL2579 GABA Receptor Alpha-6 Subunit, Human 1
GBRB1_HUMAN P18505 CHEMBL4558 GABA Receptor Beta-1 Subunit, Human 1
GBRB2_HUMAN P47870 CHEMBL1920 GABA Receptor Beta-2 Subunit, Human 1
GBRB3_HUMAN P28472 CHEMBL1847 GABA Receptor Beta-3 Subunit, Human 1
GBRD_HUMAN O14764 CHEMBL3591 GABA Receptor Delta Subunit, Human 1
GBRE_HUMAN P78334 CHEMBL4635 GABA Receptor Epsilon Subunit, Human 1
GBRG1_HUMAN Q8N1C3 CHEMBL4044 GABA Receptor Gamma-1 Subunit, Human 1
GBRG2_HUMAN P18507 CHEMBL1788 GABA Receptor Gamma-2 Subunit, Human 1
GBRG3_HUMAN Q99928 CHEMBL2739 GABA Receptor Gamma-3 Subunit, Human 1
GBRP_HUMAN O00591 CHEMBL3506 GABA Receptor Pi Subunit, Human 1
GBRT_HUMAN Q9UN88 CHEMBL2843 GABA Receptor Theta Subunit, Human 1
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 1
MTR1A_HUMAN P48039 CHEMBL1945 Melatonin Receptor 1A, Human 1
NK1R_HUMAN P25103 CHEMBL249 Neurokinin 1 Receptor, Human 1
NK1R_RAT P14600 CHEMBL4027 Neurokinin 1 Receptor, Rat 1
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 1
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 1
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 1
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 1
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 1
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 1
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 1
P97706_RAT P97706 CHEMBL4957 Sodium Channel Protein Type VI Alpha Subunit, Rat 1
PD2R_HUMAN Q13258 CHEMBL4427 Prostanoid DP Receptor, Human 1
PDYN_HUMAN P01213 CHEMBL2227 Proenkephalin B, Human 1
PE2R3_HUMAN P43115 CHEMBL3710 Prostanoid EP3 Receptor, Human 1
PE2R4_HUMAN P35408 CHEMBL1836 Prostanoid EP4 Receptor, Human 1
PF2R_HUMAN P43088 CHEMBL1987 Prostanoid FP Receptor, Human 1
PI2R_HUMAN P43119 CHEMBL1995 Prostanoid IP Receptor, Human 1
PPARG_HUMAN P37231 CHEMBL235 Peroxisome Proliferator-activated Receptor Gamma, Human 1
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 1
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 1
SCN1A_RAT P04774 CHEMBL4906 Sodium Channel Protein Type I Alpha Subunit, Rat 1
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 1
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 1
SCN3A_RAT P08104 CHEMBL4966 Sodium Channel Protein Type III Alpha Subunit, Rat 1
SCN5A_RAT P15389 CHEMBL3866 Sodium Channel Protein Type V Alpha Subunit, Rat 1
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 1
SCN8A_RAT O88420 CHEMBL2752 Sodium Channel Protein Type VIII Alpha Subunit, Rat 1
TA2R_HUMAN P21731 CHEMBL2069 Thromboxane A2 Receptor, Human 1
TSPOB_HUMAN B1AH88 CHEMBL5139 Peripheral-type Benzodiazepine Receptor, Human 1
UR2R_HUMAN Q9UKP6 CHEMBL3764 Urotensin II Receptor, Human 1
Z100491 Z100491 CHEMBL613288 Sigma 2 Receptor 1
Z104288 Z104288 CHEMBL1907594 Neuronal Acetylcholine Receptor; Alpha3/beta4 1
Z104301 Z104301 CHEMBL1907607 GABA-A Receptor; Anion Channel 1
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 1
Z50466 Z50466 CHEMBL368 Trypanosoma Cruzi 1