Alpha-1b Adrenergic Receptor, Rat (125 Compounds)


Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 125 34 28 22
Binding ≤ 1μM 88 23 19 19

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 1,203 86 55 50
ADA1B_MESAU P18841 CHEMBL3122 Alpha-1b Adrenergic Receptor, Mesau 70 7 3 5

Clustered By Gene (0)

Clustered By Organism (3)

Code Description Substances Purchasable Natural In Man
ADA1B-1-E Alpha-1b Adrenergic Receptor (cluster #1 Of 4), Eukaryotic 1,376 108 70 63
ADA1B-2-E Alpha-1b Adrenergic Receptor (cluster #2 Of 4), Eukaryotic 3 0 0 0
ADA1B-3-E Alpha-1b Adrenergic Receptor (cluster #3 Of 4), Eukaryotic 23 1 3 0
ADA1B-4-E Alpha-1b Adrenergic Receptor (cluster #4 Of 4), Eukaryotic 9 3 3 3
Uniprot Swissprot Chembl Description Number Shared
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 115
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 69
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 66
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 66
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 64
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 45
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 34
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 33
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 32
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 28
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 28
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 27
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 26
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 26
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 24
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 23
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 23
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 21
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 21
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 19
ADRB1_RAT P18090 CHEMBL3252 Beta-1 Adrenergic Receptor, Rat 19
ADRB3_RAT P26255 CHEMBL4031 Beta-3 Adrenergic Receptor, Rat 17
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 17
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 17
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 16
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 16
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 14
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 14
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 14
ADRB2_CANFA P54833 CHEMBL2289 Beta-2 Adrenergic Receptor, Canine 13
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 12
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 11
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 9
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 9
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 9
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 9
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 9
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 8
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 8
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 7
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 7
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 6
ADCY1_HUMAN Q08828 CHEMBL2899 Brain Adenylate Cyclase 1, Human 6
ADCY2_HUMAN Q08462 CHEMBL3760 Adenylate Cyclase Type II, Human 6
ADCY8_HUMAN P40145 CHEMBL2960 Adenylate Cyclase Type VIII, Human 6
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 6
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 6
5HT4R_RAT Q62758 CHEMBL4317 Serotonin 4 (5-HT4) Receptor, Rat 5
5HT5A_RAT P35364 CHEMBL4655 Serotonin 5a (5-HT5a) Receptor, Rat 5
5HT5B_RAT P35365 CHEMBL2619 Serotonin 5b (5-HT5b) Receptor, Rat 5
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 5
5HT6R_RAT P31388 CHEMBL3372 Serotonin 6 (5-HT6) Receptor, Rat 5
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 5
ADA2A_BOVIN Q28838 CHEMBL4744 Alpha-2a Adrenergic Receptor, Bovin 5
ADRB2_RAT P10608 CHEMBL3754 Beta-2 Adrenergic Receptor, Rat 5
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 5
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 5
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 5
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 4
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 4
ADA1B_MESAU P18841 CHEMBL3122 Alpha-1b Adrenergic Receptor, Mesau 4
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 4
ADRB2_HUMAN P07550 CHEMBL210 Beta-2 Adrenergic Receptor, Human 4
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 4
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 4
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 4
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 4
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 4
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 3
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 3
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 3
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 3
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 3
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 3
ACM5_RAT P08911 CHEMBL277 Muscarinic Acetylcholine Receptor M5, Rat 3
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 3
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 3
HRH2_RAT P25102 CHEMBL4654 Histamine H2 Receptor, Rat 3
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 3
HRH4_RAT Q91ZY1 CHEMBL4468 Histamine H4 Receptor, Rat 3
Q63380_RAT Q63380 CHEMBL6184 Transporter, Rat 3
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 3
SCN1A_RAT P04774 CHEMBL4906 Sodium Channel Protein Type I Alpha Subunit, Rat 3
SCN2A_RAT P04775 CHEMBL3399 Sodium Channel Protein Type II Alpha Subunit, Rat 3
SCN3A_RAT P08104 CHEMBL4966 Sodium Channel Protein Type III Alpha Subunit, Rat 3
SCN8A_RAT O88420 CHEMBL2752 Sodium Channel Protein Type VIII Alpha Subunit, Rat 3
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 2
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 2
5HT2A_MOUSE P35363 CHEMBL5377 Serotonin 2a (5-HT2a) Receptor, Mouse 2
5HT2B_MOUSE Q02152 CHEMBL2583 Serotonin 2b (5-HT2b) Receptor, Mouse 2
5HT3A_MOUSE P23979 CHEMBL4972 Serotonin 3a (5-HT3a) Receptor, Mouse 2
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 2
5HT3B_RAT Q9JJ16 CHEMBL3458 Serotonin 3b (5-HT3b) Receptor, Rat 2
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 2
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 2
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 2
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 2
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 2
ADRB3_HUMAN P13945 CHEMBL246 Beta-3 Adrenergic Receptor, Human 2
CAC1C_RAT P22002 CHEMBL3762 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rat 2
CAC1D_RAT P27732 CHEMBL4132 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Rat 2
CAC1S_RAT Q02485 CHEMBL4108 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Rat 2
DRD1_PIG P50130 CHEMBL5067 Dopamine D1 Receptor, Pig 2
DRD2_CHLAE P52702 CHEMBL5456 Dopamine D2 Receptor, Chlae 2
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 2
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 2
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 2
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 2
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 2
5HT1A_MOUSE Q64264 CHEMBL3737 Serotonin 1a (5-HT1a) Receptor, Mouse 1
5HT1F_HUMAN P30939 CHEMBL1805 Serotonin 1f (5-HT1f) Receptor, Human 1
5HT2A_PIG P50129 CHEMBL2490 Serotonin 2a (5-HT2a) Receptor, Pig 1
5HT3B_MOUSE Q9JHJ5 CHEMBL3781 Serotonin 3b (5-HT3b) Receptor, Mouse 1
5HT5A_HUMAN P47898 CHEMBL3426 Serotonin 5a (5-HT5a) Receptor, Human 1
5HT7R_MOUSE P32304 CHEMBL4764 Serotonin 7 (5-HT7) Receptor, Mouse 1
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 1
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 1
ACM4_RAT P08485 CHEMBL317 Muscarinic Acetylcholine Receptor M4, Rat 1
ADA2A_MOUSE Q01338 CHEMBL4075 Alpha-2a Adrenergic Receptor, Mouse 1
ADA2A_PIG P18871 CHEMBL2350 Alpha-2a Adrenergic Receptor, Pig 1
ADA2B_BOVIN O77700 CHEMBL3523 Alpha-2b Adrenergic Receptor, Bovin 1
ADA2B_MOUSE P30545 CHEMBL2405 Alpha-2b Adrenergic Receptor, Mouse 1
ADA2C_MOUSE Q01337 CHEMBL4826 Alpha-2c Adrenergic Receptor, Mouse 1
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 1
ADCY3_RAT P21932 CHEMBL4864 Adenylate Cyclase Type III, Rat 1
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 1
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 1
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 1
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 1
ADRB2_BOVIN Q28044 CHEMBL3373 Beta-2 Adrenergic Receptor, Bovin 1
AP2S1_RAT P62744 CHEMBL1697667 AP-2 Complex Subunit Sigma, Rat 1
D4A3N4_RAT D4A3N4 CHEMBL2679 Brain Adenylate Cyclase 1, Rat 1
EBP_HUMAN Q15125 CHEMBL4931 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human 1
ERG2_YEAST P32352 CHEMBL3224 C-8 Sterol Isomerase, Yeast 1
HRH1_CAVPO P31389 CHEMBL3943 Histamine H1 Receptor, Guinea Pig 1
HRH2_CAVPO P47747 CHEMBL2882 Histamine H2 Receptor, Guinea Pig 1
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 1
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 1
MT3_HUMAN P25713 CHEMBL1250357 Metallothionein-3, Human 1
MTR1A_HUMAN P48039 CHEMBL1945 Melatonin Receptor 1A, Human 1
MTR1B_HUMAN P49286 CHEMBL1946 Melatonin Receptor 1B, Human 1
NISCH_HUMAN Q9Y2I1 CHEMBL3923 Nischarin, Human 1
NPY1R_HUMAN P25929 CHEMBL4777 Neuropeptide Y Receptor Type 1, Human 1
NPY5R_HUMAN Q15761 CHEMBL4561 Neuropeptide Y Receptor Type 5, Human 1
PRIO_HUMAN P04156 CHEMBL4869 Prion Protein, Human 1
Q4U254_9ENTO Q4U254 CHEMBL2857 Human Rhinovirus A Protease, 9ento 1
Q72874_9HIV1 Q72874 CHEMBL243 Human Immunodeficiency Virus Type 1 Protease, 9hiv1 1
Q8CFM9_RAT Q8CFM9 CHEMBL3940 Adenylate Cyclase Type VII, Rat 1
S22A1_HUMAN O15245 CHEMBL5685 Solute Carrier Family 22 Member 1, Human 1
SC6A2_MOUSE O55192 CHEMBL2370 Norepinephrine Transporter, Mouse 1
SC6A3_MOUSE Q61327 CHEMBL2799 Dopamine Transporter, Mouse 1
SC6A4_MOUSE Q60857 CHEMBL4642 Serotonin Transporter, Mouse 1
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 1
TYTR_TRYCR P28593 CHEMBL5131 Trypanothione Reductase, Trycr 1
Z100491 Z100491 CHEMBL613288 Sigma 2 Receptor 1
Z104283 Z104283 CHEMBL1907589 Neuronal Acetylcholine Receptor; Alpha4/beta2 1